Biomarcadores hemáticos de bezerros bubalinos do nascimento até 18 meses de idade

Abstract

Maintaining health in buffalo culture is a major challenge for an efficient and productive livestock system. Thus, hematological studies in buffalo species can contribute to the diagnosis of diseases and maintenance of the health status of the herd. However, those available in the literature still do not allow establishing all the standards and normality values for the buffalo species, especially in the humid Amazonian tropics. In this context, the objective was to collect and systematize studies that evaluated the reference intervals of hematological parameters in buffaloes. The searches were located in the following databases: Science Direct, Scopus, Scielo (Scientific Electronic Library Online), Pub Med and Web of Science. The Boolean operators used were AND OR. The following terms were used to perform the searches: "Buffalo" OR "Buffaloes" AND "Blood cell" OR "Blood count" OR "Blood tests" OR "Erythrocytes" OR "Erythrogram" OR "Hematologic" OR "Hematologic profile" OR “Hematological profile” OR “Hematology” OR “Hematology profile” OR “Hemogram” OR “Leukocytes” AND “Reference intervals” OR “Reference Value”. 15,009 titles were obtained, 126 duplicates excluded, leaving a total of 14,883. To read the titles, abstracts and keywords, the number reached 180. In which 40 articles were selected to be read in full. The descriptive synthesis of the studies was built from 20 research articles selected to be part of the systematic review, published between 1982 and 2021. The researchers who sought to assess the hematological parameters in buffalo species were able t propose satisfactory results to be used as standards or reference ranges, but the fact that most studies do not analyze all the constituents of the blood count of buffaloes, highlight the need for more studies with standardized variables. In addition to the first study, it also aimed to determine the hematological biomarkers of buffalo calves from birth to 18 months. The study was carried out at the Eva Daher Abufaiad/Ufra Dairy Buffalo Farming Unit, Belém campus, Pará, using 24 buffalo animals, crossbred Murrah x Mediterranean. Calves eligible for the study were those without clinical and pathological changes at birth, determined by physical examination, alertness and vigor, rectal temperature, vital parameters, mucosal color and normal capillary refill time. From each animal, 22 harvests were taken from birth to 18 months of age. The hematological analysis was performed in an automatic calibrated for the buffalo species. Descriptive statistics were represented by the arithmetic mean and standard error of the mean (SEM) for continuous variables, and percentage (%) for the occurrence of binomial variables, with differences considered significant when P < 0.05. There was an influence of age on the constituents of the blood count, number of red blood cells, hemoglobin and packed cell volume and on the number of eosinophils (P < 0.05). There was no statistical difference on the other hematological parameters. Thus, it was found that the age factor influences the number of red blood cells, hemoglobin and globular volume and the number of eosinophils of the Hematological biomarkers of buffalo calves from birth to 18 months of age, crossbred Murrah x Mediterranean, raised in continuous stocking in the humid Amazonian tropic.