Influência de diferentes protocolos de contenção nos valores do eletrocardiograma e pressão arterial de macacos-da-noite (Aotus azarae infulatus) - Kuhl, 1820

Abstract

Feline night monkeys are small nocturnal primates, used as models for biomedical research, however there are few studies on the physiology and diseases that can afflict them. The Aotus are very susceptible to stress when manipulated and so the use of anesthetics and methods of physical restraint should be carefully evaluated before any procedure. The anesthetic protocols can significantly alter the physiological parameters, and the electrocardiogram (ECG) and measurement of blood pressure (BP) major tests for evaluation of the cardiovascular system. The objective of this study was to observe the influence of four different protocols to contain in Aotus azarae infulatus exams ECG and BP. For this, we used 10 animais, adult male, weighing 1 kg, clinically healthy, subject to protocols with contention Zoletil (ZOL), isoflurane (ISO), ketamine and midazolam (CET) and physical restraint (CF). There were no differences in ECG in ali groups, however CF group had a larger amount of electrocardiographic changes. The induction time was lower in CET, while the recovery was faster in ISO group. BP was lower in the group ISO. Heart rate (HR) measured from the pressure device in comparison to the ECG trace was similar in CF, and different in ali other groups. It was concluded that the anesthetic Zoletil promoted fewer complications in ECG and did not alter significantly the BP, being considered the best for these exams, besides that, BP machine was not safe to determine the HR and the CF group not could be considered control because presents more complications in ECG than the other protocols.